AOD 9604 (5mg)
$41.00
AOD 9604 5mg is a premium, high-purity (\ge99% HPLC-verified) synthetic analog of the C-terminal region of human growth hormone (hGH 177-191). Engineered specifically to isolate lipolytic receptor activity without elevating IGF-1 levels or altering glucose metabolism, AOD 9604 is an essential tool for laboratory studies targeting lipid metabolism, adipocyte signaling, and cartilage matrix regeneration. Supplied as a sterile lyophilized powder strictly for scientific research use.
AOD 9604 (5mg) – High-Purity Lipolytic Research Peptide
AOD 9604 (Advanced Obesity Drug 9604) is a modified, synthetic peptide fragment derived from the C-terminal region of Human Growth Hormone (hGH fragment 177–191), specifically modified with an added C-terminal tyrosine residue. Engineered to isolate the specific lipolytic (fat-reducing) properties of intact growth hormone, AOD 9604 stimulates metabolic pathways without triggering IGF-1 production, cell proliferation, or altered insulin sensitivity. Each vial provides 5mg of high-purity (\ge99% HPLC verified) lyophilized powder, formulated strictly for laboratory and in vitro scientific investigation.
Structural Features & Biological Mechanism
AOD 9604 replicates the exact domain of native Growth Hormone responsible for lipid metabolism, while avoiding the side effects associated with full-length hGH administration:
Targeted Lipolysis: Acts directly on adipocyte \beta_3-adrenergic receptors to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat storage).
IGF-1 Independent: Unlike full hGH molecules, AOD 9604 does not stimulate circulating IGF-1 elevation, preventing unwanted tissue growth or cellular proliferation signaling.
Metabolic Neutrality: Demonstrates no adverse impact on serum glucose levels or insulin sensitivity in cell and animal models.
Cartilage & Repair Signaling: Investigated for secondary extracellular matrix signaling pathways, specifically regarding chondrocyte proliferation and articular cartilage repair models.
Primary Laboratory Research Applications
Lipid Metabolism & Adipose Pathways: Utilized to map beta-adrenergic receptor interaction, intracellular cAMP activation, and glycerol release kinetics in primary adipocyte cultures.
Chondrogenic & Regenerative Studies: Studied in joint tissue models to evaluate collagen type II synthesis and cartilage repair kinetics.
Metabolic Comparative Studies: Serves as a standard control compound to compare selective C-terminal fragment activity against full-spectrum hGH signaling.
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