Melanotan 1 (10mg)
Melanotan 1 10 mg provides a high-purity, laboratory-verified lyophilized peptide manufactured under strict quality control standards in the USA. Formulated with 10 mg of pure Melanotan 1 (Melanotan I / Afamelanotide)āa synthetic linear peptide analog of endogenous alpha-melanocyte-stimulating hormone (\alpha-MSH)āthis compound is widely utilized in dermatological, photobiological, and melanocortin receptor research examining melanogenesis activation, UV photoprotection mechanisms, and receptor selectivity.
Key Specifications
Ā Active Compound: Melanotan 1 (Melanotan I / Afamelanotide)
Ā Chemical Formula: \text{C}_{78}\text{H}_{111}\text{N}_{21}\text{O}_{19}
Ā Molecular Weight: 1646.85 \text{ g/mol}
Ā Concentration: 10 mg per vial
Ā Purity Standard: Exceeds 99% (Third-Party HPLC & Mass Spectrometry Verified)
Ā Formulation: Sterile Lyophilized Powder
Ā Origin: Manufactured in USA
Ā Classification: Research Use Only
Primary Research Applications
Ā Melanocortin Receptor Binding Kinetics: Melanotan 1 acts as a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R), serving as a core benchmark in evaluating MC1R-mediated cAMP signaling in epidermal melanocytes.
Ā Melanogenesis & Photoprotection Models: Widely studied in cellular models investigating eumelanin synthesis, skin pigmentation pathways, and cellular defense mechanisms against ultraviolet (UV) radiation-induced DNA damage.
Ā Vascular & Anti-Inflammatory Signaling: Investigated for its role in non-pigmentary melanocortin signaling, including microvascular integrity, inflammatory response modulation, and cutaneous homeostasis.
PT-141 (Bremelanotide) (10mg)
PT-141 10 mg provides a high-purity, laboratory-verified lyophilized peptide manufactured under strict quality control standards in the USA. Formulated with 10 mg of pure PT-141 (Bremelanotide)āa synthetic cyclic peptide agonist of melanocortin receptors (MC3R and MC4R)āthis compound is widely utilized in neuroendocrine, behavioral, and central nervous system (CNS) signaling research examining melanocortin pathway activation, sexual behavior dynamics, and cardiovascular safety parameters.
Key Specifications
Ā Active Compound: PT-141 (Bremelanotide)
Ā Chemical Formula: \text{C}_{50}\text{H}_{68}\text{N}_{14}\text{O}_{10}
Ā Molecular Weight: 1025.2 \text{ g/mol}
Ā Concentration: 10 mg per vial
Ā Purity Standard: Exceeds 99% (Third-Party HPLC & Mass Spectrometry Verified)
Ā Formulation: Sterile Lyophilized Powder
Ā Origin: Manufactured in USA
Ā Classification: Research Use Only
Primary Research Applications
Ā Central Melanocortin Receptor Signaling: PT-141 acts primarily as a high-affinity agonist at central melanocortin-3 (MC3R) and melanocortin-4 (MC4R) receptors in the hypothalamus, serving as a primary tool to evaluate central nervous system-mediated behavioral pathways.
Ā Neuroendocrine & Behavioral Dynamics: Extensively studied in animal models to investigate non-vascular, neurogenic mechanisms modulating sexual motivation, appetitive behavior, and dopamine release in the medial preoptic area (mPOA).
Ā Vascular & Hemodynamic Safety Studies: Evaluated in cardiovascular research models to assess systemic pressor responses and transient blood pressure/heart rate variations associated with melanocortin receptor cross-reactivity.