B7-33 (6mg)
B7-33 6 mg provides a high-purity, laboratory-verified lyophilized peptide manufactured under strict quality control standards in the USA. Formulated with 6 mg of pure B7-33āa single-chain synthetic peptide functional analog of human gene-2 relaxin (H2 relaxin)āthis compound is widely utilized in cardiovascular, nephrology, and matrix biology research examining selective RXFP1 receptor signaling, extracellular matrix (ECM) remodeling, and anti-fibrotic signaling pathways without inducing tumor growth pathways.
Key Specifications
Active Compound: B7-33 (Relaxin-2 Receptor Agonist)
Chemical Formula: \text{C}_{136}\text{H}_{210}\text{N}_{40}\text{O}_{41}
Concentration: 6 mg per vial
Purity Standard: Exceeds 99% (Third-Party HPLC Verified)
Formulation: Sterile Lyophilized Powder
Origin: Manufactured in USA
Classification: Research Use Only
Primary Research Applications
Targeted Anti-Fibrotic Activity: B7-33 acts through the RXFP1 receptor to upregulate matrix metalloproteinases (MMPs) and suppress excessive collagen deposition, providing a targeted model for reversal of organ fibrosis.
Cardiovascular & Renal Remodeling: Extensively evaluated in preclinical models of heart failure, renal scarring, and vascular stiffness to assess hemodynamic regulation and arterial compliance enhancement.
Biasing RXFP1 Receptor Signaling: Investigated for its ability to preferentially stimulate pERK signaling over cAMP accumulation, preventing unwanted inotropic or proliferative side effects associated with full-length native relaxin.