HCG 5000 iu
$66.00
HCG 5000 IU is a high-purity research formulation supplied in a sterile, freeze-dried vial. Featuring HPLC-verified Human Chorionic Gonadotropin standardized to 5000 IU, each batch ensures consistent analytical purity and biological activity. Intended exclusively for laboratory protocols examining Luteinizing Hormone (LH) receptor pharmacology, cAMP intracellular signaling, and endocrine pathway dynamics. Research use only.
Description
HCG 5000 IU provides high-purity, laboratory-verified Human Chorionic Gonadotropin manufactured under strict quality control standards. Formulated at a standardized potency of 5000 International Units (IU) per vial, this complex glycoprotein hormone acts as a functional analogue to Luteinizing Hormone (LH). Engineered for accuracy and reproducibility, it serves as an essential ligand for laboratory protocols investigating LHCGR receptor binding, intracellular cyclic AMP (cAMP) signaling pathways, and steroidogenic cascades.
Key Specifications
Active Compound: Human Chorionic Gonadotropin (HCG)
Structure: Heterodimeric glycoprotein (Alpha & Beta Subunits)
Molecular Weight: Approx. 36,700 Da
Potency: 5000 IU per vial
Purity Standard: Exceeds 99% (Third-Party HPLC & Mass Spectrometry Verified)
Formulation: Sterile Lyophilized Powder
Classification: Research Use Only
Primary Research Applications
LHCGR Activation & Adenylyl Cyclase Pathways: Evaluates G-protein coupled receptor activation and downstream intracellular cAMP generation via protein kinase A (PKA) signaling.
Steroidogenic Pathway Regulation: Utilized in cellular models to measure intratesticular testosterone synthesis and Leydig cell response dynamics.
Endocrine & Gonadotropin Pharmacology: Serves as a reference ligand in comparative studies evaluating gonadotropin receptor density, desensitization kinetics, and hormonal regulation.
When designing laboratory research protocols involving Human Chorionic Gonadotropin (HCG), protocols generally fall into two distinct experimental models: continuous co-administration alongside exogenous androgen research, or post-protocol recovery (PCT) models aimed at restoring endogenous LH signaling.
Standard HCG Research Protocol Frameworks
Co-Administration Model (Maintenance Protocol):
Objective: Maintain Leydig cell responsiveness and intratesticular testosterone production during active androgen receptor saturating protocols.
Dosage Range: 250 IU to 500 IU administered subcutaneous (SC) or intramuscular (IM) 2–3 times per week (e.g., Monday/Wednesday/Friday).
Duration: Maintained continuously throughout the active compound exposure period.
Post-Protocol Recovery Model (PCT Onset Protocol):
Objective: Reactivate desensitized Leydig cells following compound cessation prior to initiating selective estrogen receptor modulator (SERM) protocols.
Dosage Range: 1,000 IU to 2,500 IU administered every 48 hours for 2 to 3 weeks.
Duration: 10–14 days immediately following the metabolic clearance of primary long-ester compounds.
Reconstitution & Handling:
Diluent: Reconstitute with Bacteriostatic Water (0.9% Benzyl Alcohol).
Storage: Once reconstituted, store at 2°C–8°C (36°F–46°F) protected from light. Stable for 30–60 days under refrigeration.
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