AICAR Peptide (50mg)
AICAR 50 mg provides a high-purity, laboratory-verified lyophilized compound manufactured under strict quality control standards in the USA. Formulated with 50 mg of pure AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) per vial, this synthetic adenosine analog is widely utilized in cellular, metabolic, and exercise physiology research investigating AMP-activated protein kinase (AMPK) activation, cellular energy homeostasis, and mitochondrial biogenesis pathways.
Key Specifications
Ā Active Compound: AICAR (Acadesine / AICA Riboside)
Ā Chemical Formula: \text{C}_{9}\text{H}_{15}\text{N}_{4}\text{O}_{8}\text{P}
Ā Concentration: 50 mg per vial
Ā Purity Standard: Exceeds 99% (Third-Party HPLC Verified)
Ā Formulation: Sterile Lyophilized Powder
Ā Origin: Manufactured in USA
Ā Classification: Research Use Only
Primary Research Applications
Ā AMP-Activated Protein Kinase (AMPK) Activation: AICAR is intracellularly phosphorylated into ZMP, an AMP mimic that directly activates AMPK without altering cellular ATP/ADP ratios, facilitating targeted metabolic research.
Ā Mitochondrial Biogenesis & Endurance Pathways: Applied in cell cultures to analyze upregulated PGC-1$\alpha$ signaling, glucose uptake enhancement, and lipid oxidation mechanisms.
Ā Ischemic & Cellular Energy Homeostasis Studies: Extensively investigated in cardiac and skeletal muscle models measuring metabolic adaptation, cellular stress response, and insulin sensitivity.