ARA-290 16mg

ARA-290 16 mg provides a high-purity, laboratory-verified lyophilized peptide manufactured under strict quality control standards in the USA. Formulated with 16 mg of pure ARA-290 (Cibinetide; Pyroglu-Glu-Gln-Glu-Arg-Glu-Arg-Ala-Glu-Ala-Lys-Glu)—a 11-amino-acid synthetic peptide derived from the erythropoietin (EPO) structure—this compound selectively targets the Innate Repair Receptor (IRR) without stimulating erythropoiesis. It is widely utilized in neurology, immunology, and tissue regeneration research investigating neuropathic pain attenuation, small nerve fiber regeneration, and inflammatory cytokine suppression.
Key Specifications
Active Compound: ARA-290 (Cibinetide / Pyroglutamate Helix B Surface Peptide)
Chemical Formula: \text{C}_{51}\text{H}_{84}\text{N}_{16}\text{O}_{21}
Concentration: 16 mg per vial
Purity Standard: Exceeds 99% (Third-Party HPLC Verified)
Formulation: Sterile Lyophilized Powder
Origin: Manufactured in USA
Classification: Research Use Only
Primary Research Applications
Selective Innate Repair Receptor (IRR) Activation: ARA-290 selectively binds the erythropoietin receptor / \beta-common receptor (\text{EPOR/}\beta\text{cR}) heterodimer to initiate anti-inflammatory and tissue-protective signaling without increasing red blood cell count or hematocrit levels.
Small Fiber Neuropathy & Peripheral Nerve Repair: Extensively studied in neuropathic disease models for its ability to promote small nerve fiber density restoration, repair damaged peripheral axons, and relieve neuropathic pain signaling.
Anti-Inflammatory & Ischemic Protection: Investigated for its inhibitory effects on pro-inflammatory cytokine cascades (\text{TNF-}\alpha, \text{IL-6}) and its protective role against ischemia-reperfusion injury in cardiovascular and metabolic tissue models.