Alprostadil 20mcg Lyophilized Powder

Alprostadil 20mcg: Premium PGE1 Lyophilized Powder for Advanced Research

Alprostadil 20mcg (chemically known as Prostaglandin E1 or PGE1) is a high-purity research compound essential for investigating vascular biology, smooth muscle physiology, and circulatory system signaling. This 20mcg lyophilized powder provides a stable, laboratory-grade platform for scientists exploring the mechanisms of direct vasodilation and the corporal veno-occlusive process.

Mechanism of Action: The Science of Vasodilation

As a synthetic analog of the naturally occurring PGE1, Alprostadil functions through a sophisticated biochemical cascade that targets vascular smooth muscle.

• Adenylate Cyclase Activation: Alprostadil binds to specific eicosanoid receptors (EP receptors) on smooth muscle cells, stimulating the enzyme adenylate cyclase.

• Intracellular cAMP Increase: This activation leads to a surge in cyclic adenosine monophosphate (cAMP) levels, a critical secondary messenger in vascular signaling.

• Smooth Muscle Relaxation: The elevation of cAMP reduces intracellular calcium concentrations, triggering the immediate relaxation of trabecular smooth muscle and the dilation of cavernosal arteries.

• Veno-Occlusive Mechanism: In urological research models, this dilation expands lacunar spaces and compresses venules against the tunica albuginea, facilitating studies on the entrapment of blood flow.

Primary Research Applications

Researchers utilize Alprostadil 20mcg across various scientific domains to study complex physiological responses:

• Vascular Physiology & Blood Flow: Investigating the impact of PGE1 on peripheral vascular resistance and systemic blood flow regulation.

• Erectile Dysfunction Models: Serving as a primary subject in studies regarding the induction and maintenance of erections, specifically for subjects unresponsive to oral PDE5 inhibitors.

• Neonatal Cardiology: Researching the maintenance of the ductus arteriosus patency in congenital heart disease models.

• Platelet & Thrombosis Studies: Analyzing the role of PGE1 in inhibiting platelet aggregation and its potential for preventing clotting in sensitive vascular environments.

Technical Specifications & Quality Assurance

To ensure reproducible results in a laboratory setting, our Alprostadil 20mcg adheres to the following standards:

• Purity: Exceeds 99.5%, verified by HPLC and Mass Spectrometry analysis.

• Format: High-stability lyophilized (freeze-dried) powder to prevent molecular degradation.

• Concentration: Precision-dosed at 20mcg per vial.

• Origin: Proudly manufactured in the USA within certified laboratory facilities.

Why Choose Our Alprostadil 20mcg?

For high-ranking research, consistency is the most important factor. Our Alprostadil 20mcg is synthesized to provide researchers with a reliable, potent compound that mirrors the bioactivity of endogenous PGE1. The lyophilized state ensures a longer shelf life and maximum bio-availability upon reconstitution, making it an ideal choice for multi-phase vascular studies.

FAQ for Researchers

What is the difference between Alprostadil and PGE1?

Alprostadil is the synthetic form of the naturally occurring Prostaglandin E1 (PGE1) found in the human body.

How should Alprostadil be stored?

To maintain peak purity, the lyophilized powder should be stored in a cool, dry environment (typically 2°C to 8°C) away from direct light.

Disclaimer: Alprostadil 20mcg is intended for laboratory research and development purposes only.